Antidepressants in neurology: a view beyond depression
Main Article Content
Abstract
The antidepressants are a group of drugs commonly used in the area of Neurology, the main problem is that their use is in many ocassions limited by the physicians to the specific treatment of depression. With the analisis of the state of the art, we intend to value the use of antidepressants beyond the daily clinic, giving an holistic view to other pathologies. In order to do that, some of the more prevalent diseases in Neurology are going to be analised, such us, Parkinson’s, Alzheimer’s,
Multiple Sclerosis, post-stroke, tension headache or migraine. The interesting thing about our contribution is to make visible that neurological problems can be treated and improve their course, evolution and prognosis with antidepressant treatment; and that this extends beyond what would be a “simple treatment of depression per se”. In this sense, the quality of life of patients, their self-determination and social participation are significantly improved when adjusting the interactions of the latest generation drugs.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
NonCommercial — You may not use the material for commercial purposes.
NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
References
Codesido ÁFQ y ML. Antidepresivos. Man del Resid Psiquiatr. 2021;
Oxman TE. Antidepressants and cognitive impairment in the elderly. Vol. 57, Journal of Clinical Psychiatry. 1996. p. 38-44.
Thompson S, Herrmann N, Rapoport MJ, Lanctôt KL. Efficacy and safety of antidepressants for treatment of depression in alzheimer’s disease: A metaanalysis. Can J Psychiatry. 2007;52(4):248-55.
Sheline YI, West T, Yarasheski K, Swarm R, Jasielec MS, Fisher JR, et al. An antidepressant decreases CSFA production in healthy individuals and in transgenic AD mice. Sci Transl Med [Internet]. 14 de mayo de 2014 [citado 1 de diciembre de 2021];6(236). Disponible en: https://www.science.org/doi/abs/10.1126/scitranslmed.3008169
McDonald WM, Richard IH, DeLong MR. Prevalence, etiology, and treatment of depression in Parkinson’s disease. Biol Psychiatry. 1 de agosto de 2003;54(3):363-75.
Liu J, Dong J, Wang L, Su Y, Yan P, Sun S. Comparative Efficacy and Acceptability of Antidepressants in Parkinson’s Disease: A Network Meta-Analysis. PLoS One [Internet]. 2 de octubre de 2013 [citado 1 de diciembre de 2021];8(10):e76651. Disponible en: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076651
Martínez C, Codirector B, Ángel M, Lozano C. ICTUS: Incidencia, factores de riesgo y repercusión.
Espárrago Llorca G, Castilla-Guerra L, Fernández Moreno MC, Ruiz Doblado S, Jiménez Hernández MD. Depresión post ictus: Una actualización. Vol. 30, Neurologia. Elsevier Doyma; 2015. p. 23-31.
Volcy Gómez M. Cefalea tipo tensional: diagnóstico, fisiopatología y tratamiento. Acta neurol colomb [Internet]. 2008 [citado 15 de noviembre de 2021]; Disponible en: https://www.acnweb.org/es/acta-neurologica/volumen-242008/77-volumen-24-numero-3-suplemento/251-cefalea-tipo-tensional-diagnosticofisiopatologia-y-tratamiento.html
Medina Ortiz O, Arango C, Ezpeleta D. Fármacos antidepresivos en el tratamiento de la cefalea tensional. Vol. 130, Medicina Clinica. Elsevier Doyma; 2008. p. 751-7.
Colombo B, Annovazzi POL, Comi G. Therapy of primary headaches: The role of antidepressants. Neurol Sci. octubre de 2004;25(SUPPL. 3).
Rueda Sánchez M. Vista de Migraña y depresión: revisión crítica de la comorbilidad [Internet]. MEDUNAB. [citado 15 de noviembre de 2021]. p. 1-6. Disponible en: https://revistas.unab.edu.co/index.php/medunab/article/view/305/288
Moreno RD, Esponda MM, Echazarreta NLR, Triano RO, Morales JLG. Esclerosis múltiple: revisión de la literatura médica. Rev la Fac Med UNAM [Internet]. 2016 [citado 15 de noviembre de 2021];55(5):26-35. Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0026-17422012000500005
Nathoo N, Mackie A. Treating depression in multiple sclerosis with antidepressants: A brief review of clinical trials and exploration of clinical symptoms to guide treatment decisions. Mult Scler Relat Disord. 1 de noviembre de 2017;18:177-80.