Relationship between functoinal mobility and polymedication for the risk of falls in the elderly
Article Sidebar
Main Article Content
Abstract
Objective: Find the correlation between the functional mobility impairments, that are contributive to the fall risk, with the polypharmacy e the consumption of psychotropic drugs. Materials and methods: It is a corretional non-experimental study and it has a convenience sample of 37 individuals with ages between 55 and 96 years old, from both genders. The study took place on the academic year of 2018/2019, in diverse institutions in Northern and Central Portugal. Functional mobility data was collected with the Timed Up and Go Test (TUG) and was also gathered information concerning the participant’s medication. For data processing and statistical analysis Statistical Package for Social Sciences (SPSS) Windows 10 was used. Results: The sample shows moderate correlations between age and the TUG score (r=0,6), the number of drugs taken (r=0,59) and the Medication Fall Risk Score (MFRS) (r=0,42). The fall ocurrence in the last 6 months is reasonbly related with the number of drugs taken (r=0,44), with the MFRS (r=0,44) and with the consumption level 3 medication, on the MFRS (r=0,39). The number of drugs taken a day has high correlation with the MSFR (r=0,86) and moderate correlation with the level 3 medication (r=0,61). The MFSR has too high correlation with the number of level 3 drugs taken (r=0,76). It turn out age correlated with the number of falls in the past 6 months and the number of level 3 drugs had no statistically significance. The same was verified in the correlation between TUG scores and the number of falls in the past 6 months, the number of drugs taken a day, the MSFR and the number of level 3 medication.
No statistically significative differences were found between individuals with and without fall risk for any variable. Conclusion: From the obtained results, we may conclude that polypharmacy and psychotropic drugs have direct influence on the fall occurrence, however they did not reveal relation with higher TUG scores and with the presence of fall risk.
Article Details
Section
Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
NonCommercial — You may not use the material for commercial purposes.
NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
How to Cite
References
AJ, C., MC, R., MM, G., RN, N., & DM, B. (1999). Psychotropic medication withdrawal and a home-based exercise program to prevent falls: a randomized, controlled trial. Journal of the American Geriatrics Society, 850–853. Retrieved from http://ezproxy.library.yorku.ca/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=rzh&AN=107231168&site=ehost-live
Beasley, B., Pharm, B. S., & Patatanian, E. (2009). Development and Implementation, 44(12), 1095–1102.
Bohannon, R. W. (2006). Reference Values for the Timed Up and Go Test: A Descriptive Meta-Analysis. Journal of Geriatric Physical Therapy, 29(2), 64.
Bushardt, R. L., Massey, E. B., Simpson, T. W., Ariail, J. C., & Simpson, K. N. (2008). Polypharmacy: misleading, but manageable. Clinical Interventions in Aging, 3(2), 383–389. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/18686760%0Ahttp://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC2546482
da Fonseca, E. P., Sá, K. N., Nunes, R. F. R.,Ribeiro Junior, A. C., Lira, S. F. B., & Pinto, E. B. (2018). Balance, functional mobility, and fall occurrence in patients with human T-cell lymphotropic virus type-1-associated myelopathy/tropical spastic paraparesis: A cross-sectional study. Revista Da Sociedade Brasileira de Medicina Tropical, 51(2), 162–167. https://doi.org/10.1590/0037-8682-0375-2017
de Jong, M. R., Van Der Elst, M., & Hartholt, K. A. (2013). Drug-related falls in older patients: Implicated drugs, consequences, and possible prevention strategies. Therapeutic Advances in Drug Safety, 4(4), 147–154. https://doi.org/10.1177/2042098613486829
Dhalwani, N. N., Fahami, R., Sathanapally, H., Seidu, S., Davies, M. J., & Khunti, K. (2017). Association between polypharmacy and falls in older adults: A longitudinal study from England. BMJ Open, 7(10), 1–8. https://doi.org/10.1136/bmjopen- 2017-016358
Fernández, M., Valbuena, C., & Natal, C. (2018). Riesgo de caídas asociado al consumo de medicamentos en la población anciana. Revista de Calidad Asistencial, (xx), 10-13. https://doi.org/10.1016/j.cali.2017.12.007
Ferreira, M. (2014). Aprova a classificação farmacoterapêutica de medicamentos. Revoga o Despacho n.o 2977 / 2014, do Secretário de Estado da Saúde.
Gómez, C., Vega-Quiroga, S., Bermejo-Pareja, F., Medrano, M. J., Louis, E. D., & Benito-Léon, J. (2015). Polypharmacy in the Elderly: A Marker of Increased Risk of Mortality in a Population-Based Prospective Study (NEDICES). International Journal of Advances in Soft Computing and Its Applications, 7(3), 126–145.
Hamza, S. A., & Abdelrahman, E. E. (2019). The relation between falls and medication use among elderly in assisted living facilities, (June 2018), 849–856. https://doi.org/10.1002/pds.4775
Hartikainen, S., Lönnroos, E., & Louhivuori, K. (2007). Medication as a risk factor for falls: Critical systematic review. Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 62(10), 1172–1181. https://doi.org/10.1093/gerona/62.10.1172
Just, K. S., Schneider, K. L., Schurig, M., Stingl, J. C., & Brockmöller, J. (2017). Falls: The adverse drug reaction of the elderly and the impact of pharmacogenetics. Pharmacogenomics, 18(13), 1281–1297. https://doi.org/10.2217/pgs-2017-0018
Jyrkkä,J., Enlund, H., Korhonen, M.J., Sulkava, R., & Hartikainen, S. (2009). Polypharmacystatusasan indicator of mortality in an elderly population. Drugs and Aging, 26(12), 1039–1048. https://doi.org/10.2165/113195 30-000000000-00000
Kalache, A. (2007). WHO Global Report on Falls Prevention in Older Age. Community Health, 53. https://doi.org/978 92 4 156353 6
Kim, J. C., Chon, J., Kim, H. S., Lee, J. H., Yoo, S. D., Kim, D. H., … Won, C. W. (2017). The association between fall history and physical performance tests in the community-dwelling elderly: A cross-sectional analysis. Annals of Rehabilitation Medicine, 41(2), 239–247. https://doi.org/10.5535/arm .2017.41.2.239
Loke, M. Y., Gan, L., & Islahudin, F. (2018). Awareness of medication related falls and preferred interventions among the...: Discovery Service for Western Governors University. Pakistan Journal of Pharmaceutical Scinces, 31(2), 359–364. Retrieved from http://eds.b.ebscohost.com.wgu.idm.oclc.org/eds/pdfviewer/pdfviewer?vid=1&sid =0949d2e5-27c0-4ebc-a542-16348fd49367%40sessionmgr120
Lord, S. R., Delbaere, K., & Sturnieks, D. L. (2018). Aging. Handbook of Clinical Neurology, 159, 157–171. https://doi.org/10.1016/B978-0-444-63916-5.00010-0
Masumoto, S., Sato, M., Maeno, T., Ichinohe, Y., & Maeno, T. (2018). Potentially inappropriate medications with polypharmacy increase the risk of falls in older Japanese patients: 1-year prospective cohort study. Geriatrics and Gerontology International, 18(7), 1064–1070. https://doi.org/10.1111/ggi.13307
Milisen, K. R. (1991). Guide de pratique clinique flamand «La prévention des chutes chez les personnes âgées résidant à domicile ». Mammalia, 55(4). https://doi.org/10.1515/mamm.1991.55.4.665
OMS, O. M. de S. (2015). Relatório Mundial de Envelhecimento e Saúde. Pestana, M. H. (n.d.). Análise de dados para ciências sociais.
Podsiadlo, D., & Richardson, S. (1991). The Timed “Up & Go”: A Test of Basic Functional Mobility for Frail Elderly Persons, 142–148. https://doi.org/10.1111/j.1532-5415.1991.tb01616.x
PORDATA. (2007). Índice de envelhecimento, 1–11. Therese, H., Steinsbekk, A., & Gerd, A. (2017). Elderly users of fall-risk-increasing drug perceptions of fall risk and the relation to their drug use – a qualitative study, 35(3), 247–255.
Torres-de Araújo,J. R., Tomaz-de Lima, R. R., Ferreira-Bendassolli, I. M., & Costa-de Lima, K. (2018). Functional, nutritional and social factors associated with mobility limitations in the elderly: A systematic review. Salud Publica de Mexico, 60(5), 579–585. https://doi.org/10.21149/9075
Watanabe, J. H. (2011). Medication Use, Falls, and Fall-Related Worry in Older Adults in the United States, 26(10), 754–763.
Ana Filipa Almeida, Vítor Pinheir a, Nuno Cor deir o World economic and social survey, 2007: development in an ageing world. (2007). Choice Reviews Online (Vol. 45). https://doi.org/10.5860/CHOICE.45-2157
Zia, A., Kamaruzzaman, S. B., & Tan, M. P. (2015). Polypharmacy and falls in older people: Balancing evidence based medicine against falls risk. Postgraduate Medicine, 127(3), 330–337. https://doi.org/10.1080/00325481.2014.996112