Communication and management of antibiotic therapy in palliative care: a narrative review

Main Article Content

P. Dias
G. Quintas
S. Maia
R. Ribeiro
D. Cunha

Abstract

Introduction: Palliative Care (PC) improves the quality of life of people with life-limiting illnesses and their families. It is considered active and coordinated care that ensures the principle of autonomy is respected. Thus, discussing the use of antibiotics in PC is of particular importance in decision-making. Objective: To understand how the communication process influences decision-making regarding the use of antibiotics in end-of-life care. Methodology: A narrative review was conducted using the databases MEDLINE Complete, CINAHL Complete, Cochrane Central Register of Controlled Trials, Cochrane Databases of Systematic Reviews, Cochrane Methodology Register, and PubMed. Results: 14 studies focused on communication about the use of antibiotics in PC were included, addressing the study objective. The data were organized into seven categories, based on Leininger’s Theory of Culture Care Diversity and Universality: communication and interaction, decision-making, culturally sensitive care, quality of care, education and training, involvement of health professionals, ethics, and responsibility. Discussion of Results: The use of antibiotics at the end of life should strictly consider the benefits, guidelines for appropriate use, and the impact on the quality of life of the person, who should be involved in the decision-making process, prioritizing the principle of autonomy and contributing to the quality of care. Communication training is essential to ensure humanized care that aligns with the values of the person. Conclusions: Effective communication that respects people’s preferences is essential for appropriate decisions in PC. The lack of clear discussions leads to decisions misaligned with people’s wishes, compromising the continuity and quality of care, emphasizing the importance of continuous training.

Article Details

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Articles

Author Biographies

P. Dias, Enfermeira Especialista em Enfermagem de Saúde Mental e Psiquiátrica do Hospital da Luz Arrábida Mestranda do 3.º Curso de Mestrado em Enfermagem Médico-Cirúrgica

Enfermeira Especialista em Enfermagem de Saúde Mental e

Psiquiátrica do Hospital da Luz Arrábida

Mestranda do 3.º Curso de Mestrado em Enfermagem Médico-Cirúrgica

G. Quintas, Enfermeira Especialista em Enfermagem Médico-cirúrgica Unidade Local de Saúde de Santo António Mestranda do 3.º Curso de Mestrado em Enfermagem Médico-Cirúrgica

Enfermeira Especialista em Enfermagem Médico-cirúrgica

Unidade Local de Saúde de Santo António

Mestranda do 3.º Curso de Mestrado em Enfermagem Médico-Cirúrgica

S. Maia, Enfermeira da Unidade Local de Saúde de Santo António Mestranda do 3.º Curso de Mestrado em Enfermagem Médico-Cirúrgica

Enfermeira da Unidade Local de Saúde de Santo António

Mestranda do 3.º Curso de Mestrado em Enfermagem Médico-Cirúrgica

R. Ribeiro, Enfermeira da Unidade Local de Saúde de Santo António Mestranda do 3.º Curso de Mestrado em Enfermagem Médico-Cirúrgica

Enfermeira da Unidade Local de Saúde de Santo António

Mestranda do 3.º Curso de Mestrado em Enfermagem Médico-Cirúrgica

D. Cunha, Projessora Adjunta convidada da Escola Superior Saúde Norte da Cruz Vermelha Portuguesa

Projessora Adjunta convidada da Escola Superior

Saúde Norte da Cruz Vermelha Portuguesa

How to Cite

Communication and management of antibiotic therapy in palliative care: a narrative review. (2025). International Journal of Developmental and Educational Psychology. Revista INFAD De Psicología., 1(1), 567-584. https://doi.org/10.17060/ijodaep.2025.n1.v1.2851

References

Almeida, G. M. F., Nascimento, T. F., Silva, R. P. L., Bello, M. P., & Fontes, C. M. B. (2021). Reflexões teóricas do cuidado transcultural de Leininger no contexto da Covid-19. Revista Gaúcha de Enfermagem, 42 (esp). https://doi.org/10.1590/1983-1447.2021.20200209

Ang, G. C., Zhang, D., & Lim, K. H. J. (2016). Differences in attitudes to end-of-life care among patients, relatives, and healthcare professionals. Singapore Medical Journal , 57(1), 22–28. https://doi.org/10.11622/smedj.2016008

Betancourt, D. A. B. (2015). Madeleine Leininger and the Transcultural Theory of Nursing. The Downtown Review, 2 (1). https://engagedscholarship.csuohio.edu/tdr/vol2/iss1/1

Boucher N. A. (2016). Direct Engagement With Communities and Interprofessional Learning to Factor Culture Into End-of-Life Health Care Delivery. American journal of public health , 106(6), 996–1001. https://doi.org/10.2105/AJPH.2016.303073

Brohard, G. (2017). Initial efficacy testing of an autobiographical memory intervention on advance care planning for patients with terminal cancer. Oncology Nursing Forum, 44(6), 751–763. https://doi.org/10.1188/17.ONF.751-763

Campos, V. F., Silva, J. M., & Silva, J. J. (2019). Comunicação em cuidados paliativos: Equipe, paciente e família. Revista Bioética , 27(4), 754–764. https://doi.org/10.1590/1983-80422019274354

Childers J., Black A., Tulsky J., & Arnold R. (2017). REMAP: A Framework for Goals of Care Conversations. Journal of Oncology Practice ,13, 844-850. https://doi.org/10.1200/JOP.2016.018796

Childers, W., White, B., & Arnold, R. (2021). «Has anything changed since then?»: A framework to incorporate prior goals-of-care conversations into decision-making for acutely ill patients. Journal of Pain and Symptom Management , 61(4), 864-869. https://doi.org/10.1016/j.jpainsymman.2020.10.030

Crespo, S., Vicente, C., Amendoeira, J., & Figueiredo, M. C. B. (2014). Teoria da diversidade e universalidade do cuidado cultural: Análise segundo o método sintético de McEwen e Wills. Revista da UIIPS , 2 (5), 128.

Graça, C., Correia, I., & Pereira, J. G. (2019). Infeção em fim de vida: Há benefício da terapêutica antibiótica? Revista da Sociedade Portuguesa de Medicina Interna, 26(4). https://doi.org/10.24950/rspmi/P.Vista/126/19/4/2019

Hart, E., Snape, S., & Thomson, R. (2020). Palliative outpatient parenteral antibiotic therapy: A review of 5 years of patient data. JAC-Antimicrobial Resistance , 2(3), dlaa052. https://doi.org/10.1093/jacamr/dlaa052

Henckemaier, L., Siewert, J. S., Tonnera, L. C. J., Alvarez, A. M., Meirelles, B. H. S., & Nitschke, R. G. (2014). Cuidado transcultural de Leininger na perspectiva dos programas de pós-graduação em enfermagem: revisão integrativa. Revista Ciência & Saúde, 7 (2), 85-91.

Hojman, M., Basombrío, A., Di Líbero, E., Scapellato, P., Clara, L., de Vedia, L., & Comisión de Uso Adecuado de Antibióticos y otros Recursos de la Sociedad Argentina de Infectología (SADI). (2020). Antibioticoterapia en estadios finales de la vida. Actualizaciones en Sida e Infectología, 28(102), 2 - 12. https://doi.org/10.52226/revista.v28i102.33

Hung, K. C., Lee, L. W., Liew, Y. X., Krishna, L., Chlebicki, M. P., Chung, S. J., & Kwa, A. L. H. (2022). Antibiotic stewardship program (ASP) in palliative care: Antibiotics, to give or not to give. European Journal of Clinical Microbiology & Infectious Diseases , 41(1), 29– 36. https://doi.org/10.1007/s10096-021-04325-z

Juthani-Mehta, M., Malani, N., & Mitchell, L. (2015). Antimicrobials at the End of Life: An Opportunity to Improve Palliative Care and Infection Management. JAMA , 314(19), 2017–2018. https://doi.org/10.1001/jama.2015.13080

Karlin, D., Pham, C., Furukawa, D., Kaur, I., Martin, E., Kates, O., & Vijayan, T. (2024). State-of-the-Art Review: Use of Antimicrobials at the End of Life. Clinical infectious diseases. 78(3), e27–e36. https://doi.org/10.1093/cid/ciad735

Kilgore, C. (2022). Formulating and communicating prognoses: Tools and techniques. Caring for the Ages , 18(6), 5-6. https://www.caringfortheages.com/action/showPdf?pii=S1526-4114%2822%2900190-1

Klomstad, N., Pedersen, R., & Førde, R. (2018). Involvement in decisions about intravenous treatment for nursing home patients: Nursing homes versus hospital wards. BMC Medical Ethics, 19, Article 34. https://doi.org/10.1186/s12910-018-0258-5

Koon, E. K., & Heng, C. P. (2016). Antibiotic use in the last two weeks of life for home hospice patients in Singapore. European Journal of Palliative Care, 23(6), 299-303.

Lei nº 52/2012 Lei de Bases dos Cuidados Paliativos. (2012) Diário da República nº. 172, Série I de 2012-09-05

Lenardt, M. H., Michel, T., Betiolli, S. E., Seima, M. D., Baran, F. D. P., & Brito, C. S. (2021). Produção de conhecimentos fundamentados na Teoria da Diversidade e Universalidade do Cuidado Cultural: Pesquisa documental. Revista Brasileira de Enfermagem , 74 (3), e20200732. https://doi.org/10.1590/0034-7167-2020-0732

Macedo, F., Nunes, C., Ladeira, K., Pinho, F., Saraiva, N., Bonito, N., Pinto, L., & Gonçalves, F. (2018). Antimicrobial therapy in palliative care: An overview. Supportive Care in Cancer , 26(5), 1361–1367. https://doi.org/10.1007/s00520-018-4090-8

Marra, A. R., Puig-Asensi, M., Balkenende, E., Livorsi, D. J., Goto, M., & Perencevich, E. N. (2021). Antibiotic use during end-of-life care: A systematic literature review and meta-analysis. Infection control and hospital epidemiology , 42(5), 523–529. https://doi.org/10.1017/ice.2020.1241

Melo, L. P. (2010). A contemporaneidade da Teoria do Cuidado Cultural de Madeleine Leininger: uma perspectiva geo-histórica. Ensaios e Ciência: Ciências Biológicas, Agrárias e da Saúde, 14 (2), 21-32.

Moen, M. K., Løhre, E. T., Jakobsen, G., Thronæs, M., & Klepstad, P. (2022). Antibiotic therapy in integrated oncology and palliative cancer care: An observational study. Cancers, 14(7), 1602. https://doi.org/10.3390/cancers14071602

Oriá, M. O. B., Ximenes, L. B., & Alves, M. D. S. (2005). Madeleine Leininger e a teoria da diversidade e universalidade do cuidado cultural–um resgate histórico. Online Brazilian Journal of Nursing, 4 (2), 24-30. https://www.redalyc.org/pdf/3614/361453969005.pdf

Reinhardt, J. P., Boerner, K., & Downes, D. (2015). The positive association of end-of- life treatment discussions and care satisfaction in the nursing home. Journal of Social Work in End-of-Life & Palliative Care, 11(3-4), 307–322. https://doi.org/10.1080/15524256.2015.1107805

Reinhardt, J. P., Downes, D., Cimarolli, V., & Bomba, P. (2017). End-of-life conversations and hospice placement: Association with less aggressive care desired in the nursing home. Journal of Social Work in End-of-Life &

Palliative Care, 13(1), 61-81. https://doi.org/10.1080/15524256.2017.1282919

Ribeiro, C., & Martinez, M. (2021). Cuidados Paliativos: a importância do trabalho em equipa e aliança terapêutica. Revista Portuguesa de Oncologia , 2(1), 25–29. https://doi.org/10.57678/rpo.13

Seaton, R. A., Cooper, L., Fairweather, J., Fenning, S., Ferguson, L., Galbraith, S., & Sneddon, J. (2021). Antibiotic use towards the end of life: Development of good practice recommendations. BMJ Supportive & Palliative Care , 11(3), 323-329. https://doi.org/10.1136/bmjspcare-2020-002732

World Health Organization. (2002). National cancer control programmes : policies and managerial guidelines . 2nd ed. World Health Organization. https://iris.who.int/handle/10665/42494